
刘洪秀,教授,博士生导师,海南大学高层次人才。深耕环境健康与人工智能交叉前沿领域,致力于新型环境污染物的人群健康效应和干预措施研究。擅长将暴露组学检测技术、多组学大数据分析与人工智能算法深度融入基础与应用研究,构建了从污染物暴露组解析、分子机制到健康风险预警的完整体系,多项核心成果被美国环境保护署(EPA)等机构采纳,作为污染物人体健康风险评估、饮用水 PFAS 最大容受剂量目标值等权威文件的核心科学依据。秉持科研、育人价值相融的理念,在培养环境健康领域复合型、实战型人才方面积累了丰富经验。
【硕士/博士招收方向】
现面向环境、医学、公共卫生、生命、数统、计算机等相关专业诚招硕士、博士研究生,研究方向紧扣环境污染物与儿童健康领域前沿科学问题,贴合健康中国战略需求,具体研究内容示例:
生命早期环境暴露对儿童神经/代谢/呼吸疾病的效应解析与风险评估
关键环境因素致儿童健康损害的分子机制挖掘与关键靶点识别
基于 AI 的儿童疾病环境诱因筛选、大模型预测及风险预警体系研发
天然因子的毒性拮抗作用研究与儿童健康损害早期干预方案开发
【学习经历】
2014.09-2019.07 华中科技大学同济医学院公共卫生学院环境卫生专业,获博士学位
2020.01-2021.02 美国纽约大学 Langone 医学院儿科系,博士后研究
2021.03-2021.12 华中科技大学同济医学院公共卫生学院环境卫生专业,博士后研究
【工作经历】
2022.01-2025.01 华中科技大学 同济医学院,讲师,硕士生导师
2025.02-2025.11 华中科技大学 同济医学院,副教授,博士生导师
2025.12 - 至今 海南大学环境科学与工程学院 环境健康系,教授、博士生导师
【科研项目】
海南大学高层次人才创新基金,2025.12-2030.12,100 万元,在研,主持
国家自然科学基金面上项目(42477463), 2025.01-2028.12,47 万元,在研,主持
国家自然科学基金重点项目(22236001), 2023.01-2027.12,280万元,在研,参与
国家自然科学基金青年项目(22006046),2021.01-2023.12,24 万元,结题,主持
华中科技大学自主创新基金, 2024.10-2026.10,10 万元,在研,主持
中国博士后基金面上项目(2019M662645),8 万元,结题,主持
广西环境暴露组学与全生命周期健康重点实验室开放式课题(2023-GKLEH-02),2023.10-2025.09,结题,主持
孕妇儿童健康与暴露科学重点实验室开放基金课题资助项目(ZYGW-KF[2024]02),2024.11.1 -2026.10.31,在研,主持
华中科技大学研究生教学改革项目, 2023.06-2024.06,结题,主持
华中科技大学研究生教学改革研究项目(2025YB012),2025.10-2027.06,在研,主持
【代表论文】
[1] Hongxiu Liu†,*, Kress AM†, er.al., Trasande Leonardo; program collaborators for ECHO. Racial and ethnic disparities in environmental chemical exposures and hypertensive disorders of pregnancy: The ECHO-wide cohort study. Environmental Pollution 2026. 1
[2] Zhang J†, Liu H†, et. al., Xu S, Cai Z. Patterns, variability, and predictors of p-phenylenediamine quinones and parent p-phenylenediamines in pregnant women across three trimesters. Environmental International. 2025 Sep;203:109729.
[3] He Sen†, Wang Jinyu†, et. al., Hongxiu Liu*, Shunqing Xu*. Maternal oxidative stress throughout pregnancy and early childhood neurodevelopment at different stages: insights from a prospective cohort study.BMC Medicine. 2025.08
[4] Yun Huang, Zhenxian Jia, …, Hongxiu Liu*. Prenatal Exposure to Per- and Polyfluoroalkyl Substances and ASD-Related Symptoms in Early Childhood: Mediation Role of Steroids. Environmental Science & Technology,2024.09.
[5] Xinmei Chen†, Hongxiu Liu†, …, Wenxin Zhang, Fetal weight growth trajectories and childhood development: a population-based cohort study. Science Bulletin, 2024.09.
[6] Xinmei Chen†, Hongxiu Liu†, …, Shunqing Xu. First‑trimester fetal size, accelerated growth in utero, and child neurodevelopment in a cohort study. BMC Medicine. 2024.04.
[7] Hongxiu Liu #, Yitao Pan #, Shuna Jin, Xiaojie Sun, Yangqian Jiang, Yuyan Wang, Akhgar Ghassabian, Yuanyuan Li, Wei Xia, Qianqian Cui, Bin Zhang, Aifen Zhou, Jiayin Dai *, Shunqing Xu *. Associations between six common per- and polyfluoroalkyl substances and estrogens in neonates of China. Journal of hazardous materials 2021, 407, 124378.
[8] Hongxiu Liu # , Yitao Pan # , Shuna Jin , Yuanyuan Li , Liuqing Zhao , Xiaojie Sun , Qianqian Cui , Bin Zhang , Tongzhang Zheng , Wei Xia , Aifen Zhou , Anna Maria Campana , Jiayin Dai * , Shunqing Xu *, Associations of per-/polyfluoroalkyl substances with glucocorticoids and progestogens in newborns. Environment international 2020, 140, 105636.
[9] Hongxiu Liu # , Jiufeng Li #, Wei Xia , Bin Zhang , Yang Peng , Yuanyuan Li , Yanqiu Zhou , Jing Fang , Hongzhi Zhao , Yangqian Jiang , Wenyu Liu , Xiaojie Sun , Cheng Hu , Zongwei Cai * , Shunqing Xu *, Blood pressure changes during pregnancy in relation to urinary paraben, triclosan and benzophenone concentrations: A repeated measures study. Environment international 2019, 122, 185-192.
[10] Yanqiu Zhou #, Hongxiu Liu # , Jiufeng Li , Shunqing Xu , Yuanyuan Li , Hongzhi Zhao , Hangbiao Jin , Wenyu Liu , Arthur C K Chung , Yanjun Hong , Xiaojie Sun , Yangqian Jiang , Wenxin Zhang , Jing Fang , Wei Xia *, Zongwei Cai *. Profiles, variability, and predictors of urinary benzotriazoles and benzothiazoles in pregnant women from Wuhan, China. Environment international 2018, 121, (Pt 2), 1279-1288.
[11] Hongxiu Liu #, YuyanWang, Kurunthachalam Kannan, Mengling Liu, Hongkai Zhu, Yu Chen, Linda G. Kahn, Melanie H.Jacobson, Bo Gu, Shilpi Mehta-Lee, Sara G.Brubaker, Akhgar Ghassabian *, LeonardoTrasande. Determinants of phthalate exposures in pregnant women in New York City. Environmental research 2022, 212, 113203.
[12] Hongxiu Liu *, Anna Maria Campana , Yuyan Wang , Kurunthachalam Kannan , Mengling Liu , Hongkai Zhu , Shilpi Mehta-Lee , Sara G Brubaker , Linda G Kahn , Leonardo Trasande , Akhgar Ghassabian, Organophosphate pesticide exposure: Demographic and dietary predictors in an urban pregnancy cohort. Environmental pollution 2021, 283, 116920.
[13] Fengzhen Cui#, Hongxiu Liu #, Yuanyuan Li, Tong-Zhang Zheng, Shunqing Xu, Wei Xia, Xia Sheng. Association of exposure to per- and polyfluoroalkyl substances with hemoglobin and hematocrit during pregnancy. Ecotoxicology and environmental safety. 2022 Dec 15;248:114319.
[14] Hongxiu Liu, Jiaqiang Liao , Yangqian Jiang , Bin Zhang , Huifang Yu , Jiawei Kang , Cheng Hu , Yuanyuan Li , Shunqing Xu *, Maternal exposure to fine particulate matter and the risk of fetal distress. Ecotoxicology and environmental safety 2019, 170, 253-258.
[15] Jing Fang #, Hongxiu Liu # , Hongzhi Zhao , Yanqiu Zhou , Shunqing Xu * , Zongwei Cai *. Association of in utero hexachlorocyclohexane exposure with gestational age. Ecotoxicology and environmental safety 2019, 174, 263-269.
[16] 曹秀丽,王晶宇,李媛媛,刘洪秀*.妊娠期多种环境化合物暴露与出生体重的关联[J].中华疾病控制杂志,2025,29(02):132-138. (北大核心)
[17] 黄韵,孙小杰,李媛媛,徐顺清,刘洪秀*. 孕期甲状腺激素敏感性与出生结局关系的队列研究[J].中华疾病控制杂志, 2023,27(09):998-1002.(北大核心)
[18] 肖显赫,陈磊,…,刘洪秀*. 孕期血压与2岁儿童神经发育关联的前瞻性出生队列研究[J]. 中华预防医学杂志, 2024,58(9) : 1302-1310. (北大核心,卓越期刊)
# First authors * Corresponding author
【参编标准】
参编全国卫生行业标准《环境化学污染物参考剂量推导技术指南 (WS/T 10006-2023)》
参编全国团体标准《环境与健康队列调查技术规范 (T/CSES 62-2022)》
参编武汉有害生物防制协会团体标准《有害生物防制与消毒服务机构服务能力评定 - 集中空调通风系统清洗消毒》
【学术兼职】
英文期刊,Hygiene and Environmental Health Advances,青年编委
Journal of Environmental Exposure Assessment客座编辑(主持 “AI in Environmental Exposure and Health” 特刊)
Eco-Environment & Health期刊 2022 年度优秀审稿人
【联系方式】
海南省海口市人民大道58号海南大学海甸校区热带作物国家重点实验室中心
lhx@hainanu.edu.cn; lhxusc@126.com